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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Cash Flows From Operating Activities:    
Net income (loss) $ (2,187) $ 14,128
Adjustments to reconcile net income to net cash used in operating activities:    
Depreciation and amortization 7,858 5,536
Realized gain on marketable securities 0 (107)
Gain upon divestiture of assets to Turing Pharmaceuticals 0 (914)
Deferred income tax benefit (12,286) (40,021)
Interest income from notes receivable (1,285) 0
Non-cash interest expense 1,179 1,154
Amortization of premiums on marketable securities 666 0
Amortization of debt discount and deferred financing costs 326 1,010
Lease liability 0 (125)
Legal accrual reversal (2,967) 0
Bargain purchase gain 0 (49,063)
Share based compensation 14,286 10,567
Derivative financial instruments, warrants, issued, recorded in interest expense 0 1,050
Change in estimated fair value of liability classified warrants (5,277) 66,171
Change in estimated fair value of contingent consideration 5,485 113
Payments related to change in fair value of contingent consideration (550) (90)
Changes in operating assets and liabilities, net of business acquisitions:    
Accounts receivable (4,104) (3,508)
Inventory (174) (640)
Prepaid expenses and other current assets (1,197) (420)
Accounts payable and accrued expenses 650 (3,417)
Net cash provided by operating activities 423 1,424
Cash Flows From Investing Activities:    
Purchase of fixed assets (24) (29)
Cash paid for intangible assets (4,881) (2,497)
Proceeds from the sale/maturity of marketable securities 59,874 282
Purchase of marketable securities (68,517) 0
Cash received upon divestiture of asset 0 3,311
Cash paid upon acquisition, net of cash acquired (500) (33,430)
Net cash used in investing activities (14,048) (32,363)
Cash Flows From Financing Activities:    
Payment of guaranteed minimum royalty (1,000) (1,000)
Proceeds from exercise of warrants 90 586
Payment of other liability (500) (500)
Proceeds from exercise of stock options 1,572 2,669
Excess benefit related to stock compensation (236) 0
Proceeds received from issuance of common stock 0 149,454
Financing costs from issuance of common stock 0 (9,500)
Net cash used in (provided by) financing activities (2,843) 140,481
Effect of exchange rate changes on cash (182) 0
Net change in cash (16,650) 109,542
Cash, beginning of year 37,805 18,204
Cash, end of period 21,155 127,746
Manchester    
Cash Flows From Financing Activities:    
Payment of acquisition-related contingent consideration (2,125) (1,228)
Asklepion    
Cash Flows From Financing Activities:    
Payment of acquisition-related contingent consideration $ (644) $ 0