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INTANGIBLE ASSETS - Additional Information (Details) - USD ($)
$ in Thousands
9 Months Ended 12 Months Ended
Mar. 31, 2015
Mar. 26, 2014
Sep. 30, 2015
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
May. 29, 2014
Finite-Lived Intangible Assets [Line Items]              
Net Book Value       $ 161,536 $ 94,265    
Impairment of intangible assets       4,710 0 $ 0  
Finite-lived intangible asset       $ 179,096 99,867    
Remaining weighed average period of amortization (in years)       11 years 22 days      
Cash paid upon consummation       $ 33,430 29,150 0  
Other Expense              
Finite-Lived Intangible Assets [Line Items]              
Impairment of intangible assets     $ 4,700        
Minimum              
Finite-Lived Intangible Assets [Line Items]              
Assets useful life (in years)       1 year      
Maximum              
Finite-Lived Intangible Assets [Line Items]              
Assets useful life (in years)       16 years      
Manchester Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Cash paid upon consummation   $ 29,150          
Asklepion Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Discount rate percentage       19.00%      
Cash paid upon consummation $ 33,430            
Common stock shares issued (in shares) 661,279            
Value of common stock $ 15,844            
Ligand License Agreement              
Finite-Lived Intangible Assets [Line Items]              
Net Book Value           2,500  
Require To Make Substantial Payments Payable Upon Achievement Of Milestones           $ 105,500  
Payment of amendment consideration       $ 1,000      
Finite-lived intangible asset       3,300      
Ligand License Agreement | Minimum              
Finite-Lived Intangible Assets [Line Items]              
Annual Royalty Percentage           15.00%  
Ligand License Agreement | Maximum              
Finite-Lived Intangible Assets [Line Items]              
Annual Royalty Percentage           17.00%  
Chenodal Product Rights              
Finite-Lived Intangible Assets [Line Items]              
Net Book Value       60,360      
Finite-lived intangible asset       $ 67,849      
Assets useful life (in years)       16 years      
Product rights              
Finite-Lived Intangible Assets [Line Items]              
Net Book Value         67,952    
Finite-lived intangible asset         $ 71,372    
Assets useful life (in years)         16 years    
Product rights | Manchester Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Intangible assets with definite lives   $ 71,372          
Assets useful life (in years)   16 years   16 years      
Product rights | Asklepion Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Assets useful life (in years) 10 years            
Trade Name              
Finite-Lived Intangible Assets [Line Items]              
Net Book Value       $ 0 $ 41    
Finite-lived intangible asset       $ 175 $ 175    
Assets useful life (in years)       1 year 1 year    
Trade Name | Manchester Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Intangible assets with definite lives   $ 175   $ 200      
Assets useful life (in years)   1 year   1 year      
Customer relationships              
Finite-Lived Intangible Assets [Line Items]              
Net Book Value       $ 332 $ 372    
Finite-lived intangible asset       $ 403 $ 403    
Assets useful life (in years)       10 years 10 years    
Customer relationships | Manchester Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Intangible assets with definite lives   $ 403   $ 400      
Assets useful life (in years)   10 years   10 years      
Vecamyl              
Finite-Lived Intangible Assets [Line Items]              
Finite-lived intangible asset       $ 3,600      
Thiola License Agreement              
Finite-Lived Intangible Assets [Line Items]              
Assets useful life (in years)         10 years    
Remaining weighed average period of amortization (in years)         8 years 4 months 24 days    
Thiola License Agreement | Mission Pharmacal Company              
Finite-Lived Intangible Assets [Line Items]              
Present value of guaranteed minimum royalties payable       $ 10,900      
Discount rate percentage       11.00%      
Mission an up-front license fee             $ 3,000
Guaranteed minimum royalties             $ 2,000
Thiola License Agreement | Mission Pharmacal Company | Other Current Liabilities              
Finite-Lived Intangible Assets [Line Items]              
Guaranteed minimum royalties       $ 800      
Thiola License Agreement | Mission Pharmacal Company | Other Noncurrent Liabilities              
Finite-Lived Intangible Assets [Line Items]              
Guaranteed minimum royalties       10,100      
Thiola Asset              
Finite-Lived Intangible Assets [Line Items]              
Net Book Value       21,340 $ 14,179    
Finite-lived intangible asset       $ 24,133 $ 15,049    
Assets useful life (in years)       10 years 10 years    
United States | Asklepion Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Capitalized economic interest $ 75,900            
International | Asklepion Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Capitalized economic interest 7,300            
Purchase Agreement | Asklepion Pharmaceuticals LLC              
Finite-Lived Intangible Assets [Line Items]              
Value of common stock $ 9,000