CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Income Statement [Abstract]
Net product sales	$ 99,892	$ 28,203	$ 0
Operating expenses:
Cost of goods sold	2,185	571	0
Research and development	50,426	47,795	7,084
Selling, general and administrative	79,541	59,645	17,689
Change in fair value of contingent consideration	13,778	0	0
Impairment of intangible assets	4,710	0	0
Total operating expenses	150,640	108,011	24,773
Operating loss	(50,748)	(79,808)	(24,773)
Other expenses, net:
Litigation settlement gain	15,500	0	0
Other income (expense), net	(296)	2,352	370
Interest expense, net	(7,748)	(7,435)	(46)
Debt early payment penalty	(2,250)	0	0
Loss on extinguishment of debt	(4,151)	0	0
Finance expense	(600)	(4,721)	0
Change in fair value of derivative instruments	(33,307)	(23,786)	(10,100)
Gain on sale of assets	140,004	0	0
Bargain purchase gain	49,063	0	0
Total other income (expense), net	156,215	(33,590)	(9,776)
Income (loss) before benefit (provision) for income taxes	105,467	(113,398)	(34,549)
Income tax benefit (provision)	11,770	2,460	(76)
Net income (loss)	$ 117,237	$ (110,938)	$ (34,625)
Net income (loss) per common share, basic (in dollars per shares)	$ 3.49	$ (4.43)	$ (2.44)
Net income (loss) per common share, diluted (in dollars per shares)	$ 3.17	$ (4.43)	$ (2.44)
Weighted average common shares outstanding, basic (in shares)	33,560,249	25,057,509	14,205,264
Weighted average common shares outstanding, diluted (in shares)	37,581,439	25,057,509	14,205,264
Comprehensive income (loss):
Net income (loss)	$ 117,237	$ (110,938)	$ (34,625)
Foreign currency translation loss	(40)	0	0
Unrealized gain (loss) on sale of marketable securities	(4,927)	4,396	(110)
Comprehensive income (loss)	$ 112,270	$ (106,542)	$ (34,735)