CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)	6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019
Cash Flows From Operating Activities:
Net loss	$ (25,260,000)	$ (79,678,000)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	11,507,000	9,742,000
Non-cash interest expense	893,000	798,000
Amortization (accretion) of discounts/premiums on investments, net	337,000	(580,000)
Amortization of debt discount and issuance costs	5,147,000	4,933,000
Provision for Inventory	662,000	(358,000)
Share-based compensation	11,474,000	11,947,000
ESPP expense	390,000	345,000
Change in fair value of contingent consideration	2,363,000	(11,478,000)
Payments related to change in fair value of contingent consideration	(8,674,000)	(2,767,000)
Write off of IPR&D intangible assets	0	25,500,000
Unrealized foreign currency transaction gain (loss)	(222,000)	14,000
Other	496,000	60,000
Changes in operating assets and liabilities:
Accounts receivable	3,979,000	(2,396,000)
Inventory	(875,000)	918,000
Tax receivable	(18,714,000)	0
Other current and non-current operating assets	(2,508,000)	(10,101,000)
Accounts payable and accrued expenses	(16,407,000)	6,305,000
Other current and non-current operating liabilities	(196,000)	7,195,000
Net cash used in operating activities	(35,608,000)	(39,601,000)
Cash Flows From Investing Activities:
Purchase of fixed assets	(518,000)	(21,000)
Cash paid for intangible assets	(8,532,000)	(7,347,000)
Proceeds from the sale/maturity of debt securities	153,146,000	115,998,000
Purchase of debt securities	(36,743,000)	(94,812,000)
Net cash provided by investing activities	107,353,000	13,818,000
Cash Flows From Financing Activities:
Payment of acquisition-related contingent consideration	(6,101,000)	(1,722,000)
Payment of guaranteed minimum royalty	(1,050,000)	(1,034,000)
Proceeds from exercise of stock options	431,000	317,000
Proceeds from issuance of common stock, net of issuance costs	108,644,000	0
Proceeds from issuances under employee stock purchase plan	1,098,000	1,005,000
Net cash provided by (used in) financing activities	103,022,000	(1,434,000)
Effect of exchange rate changes on cash	(33,000)	1,000
Net change in cash and cash equivalents	174,734,000	(27,216,000)
Cash and cash equivalents, beginning of year	62,436,000	102,873,000
Cash and cash equivalents, end of period	$ 237,170,000	$ 75,657,000