CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands	6 Months Ended
Jun. 30, 2018	Jun. 30, 2017
Cash Flows From Operating Activities:
Net loss	$ (40,707)	$ (24,319)
Adjustments to reconcile net income to net cash provided by operating activities:
Depreciation and amortization	8,991	8,721
Deferred income tax benefit	0	(5,420)
Interest income from notes receivable	0	(651)
Non-cash interest expense	767	1,325
Amortization of premiums on marketable securities	647	602
Loss on disposal of fixed assets	0	305
Provision for Inventory	378	83
Share based compensation	10,160	14,332
Change in fair value of contingent consideration	5,786	6,628
Payments related to change in fair value of contingent consideration	(5,563)	(553)
Provision for doubtful accounts	(13)	410
Unrealized foreign currency transaction gain	(214)	559
Other	537	197
Changes in operating assets and liabilities, net of business acquisitions:
Accounts receivable	1,431	4,685
Inventory	(433)	(212)
Other current and non-current operating assets	637	(12)
Accounts payable and accrued expenses	(2,811)	(3,458)
Other current and non-current operating liabilities	2,485	(45)
Net cash provided by (used in) operating activities	(17,494)	2,059
Cash Flows From Investing Activities:
Purchase of fixed assets	(601)	(1,056)
Cash paid for intangible assets	(11,389)	(6,278)
Proceeds from the sale/maturity of marketable securities	63,565	43,940
Purchase of marketable securities	(29,519)	(36,213)
Proceeds from maturity of note receivable	0	47,500
Cash paid for investments - equity	15,000	0
Net cash provided by investing activities	7,056	47,893
Cash Flows From Financing Activities:
Payment of acquisition-related contingent consideration	(7,947)	(3,254)
Payment of guaranteed minimum royalty	(1,000)	(1,000)
Payment of other liability	(500)	(500)
Proceeds from exercise of warrants	2,140	0
Proceeds from exercise of stock options	6,890	3,003
Other financing activities	800	0
Net cash provided by (used in) financing activities	383	(1,751)
Effect of exchange rate changes on cash	(34)	63
Net change in cash	(10,089)	48,264
Cash, beginning of year	99,394	41,002
Cash, end of period	$ 89,305	$ 89,266

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Amount of cash outflow for the payment of debt classified as other.

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The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method.

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