X0306 4 2018-07-26 0 0001438533 Retrophin, Inc. RTRX 0001579649 Rosenberg Noah L. C/O RETROPHIN, INC. 3721 VALLEY CENTRE DRIVE, SUITE 200 SAN DIEGO CA 92130 0 1 0 0 Chief Medical Officer Common Stock 2018-07-26 4 A 0 10000 0.00 A 10000 D Employee stock option (right to buy) 28.58 2018-07-26 4 A 0 65000 0.00 A 2028-07-25 Common Stock 65000 65000 D Performance-based restricted stock units 2018-07-26 4 A 0 10000 0.00 A Common Stock 10000 10000 D One-fourth of the shares subject to the stock option vest and become exercisable on the first anniversary of the date of grant, and the remaining shares vest in 36 equal monthly installments thereafter. Each restricted stock unit represents a contingent right to receive one share of the Common Stock of the Issuer. This grant will vest upon the later of (i) 12 months from the date of grant, and (ii) the achievement of specified clinical and regulatory milestones, provided that the grant will expire on May 10, 2022 to the extent the specified clinical and regulatory milestones are not achieved by such date. /s/ Elizabeth E. Reed, Attorney-in-Fact 2018-07-30