Note 15 - Income Taxes (Details Textual) - USD ($) Pure in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Effective Income Tax Rate Reconciliation, Percent, Total	0.00%	0.00%
Deferred Tax Assets, Valuation Allowance	$ 104,361	$ 95,256
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount	9,105
Deferred Tax Assets, Operating Loss Carryforwards, Domestic	257,535
Deferred Tax Assets, Operating Loss Carryforwards, State and Local	173,657
Deferred Tax Assets, Operating Loss Carryforwards, Foreign	$ 70,922
Federal Net Operating Loss Carryforwards, Expiration Period Minimum (Year)	5 years
Federal Tax Credit CarryForward, Expiration Period, Maximum (Year)	20 years
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total	$ 0	$ 0
State Tax Credit Carry Forward, Expiration Period, Minimum (Year)	5 years
Foreign Tax Credit Carry Forward, Expiration Period, Minimum (Year)	5 years
Domestic Tax Jurisdiction [Member]
Open Tax Year	2021 2022 2023
Domestic Tax Jurisdiction [Member] | Research Tax Credit Carryforward [Member]
Tax Credit Carryforward, Amount	$ 14,746
State and Local Jurisdiction [Member]
Open Tax Year	2021 2022 2023
Foreign Tax Jurisdiction [Member]
Open Tax Year	2023