Composition of Certain Financial Statement Items - Summary of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Property, Plant and Equipment [Line Items]
Total cost	$ 99,555	$ 88,955
Less: accumulated depreciation and amortization	(49,169)	(38,933)
Total property and equipment, net	50,386	50,022
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total cost	25,245	22,834
Office furniture and equipment
Property, Plant and Equipment [Line Items]
Total cost	9,943	9,876
Computer equipment and software
Property, Plant and Equipment [Line Items]
Total cost	11,544	12,219
Manufacturing and scientific equipment
Property, Plant and Equipment [Line Items]
Total cost	$ 52,823	$ 44,026