CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 71,181	$ 94,613
Short-term investments	552,630	390,323
Accounts receivable, net	110,725	82,195
Inventories	68,551	63,721
Prepaid and other current assets	8,433	6,383
Total current assets	811,520	637,235
Property and equipment, net	50,386	50,022
Operating lease right-of-use assets	27,503	19,773
Other long-term assets	15,728	9,385
Total assets	905,137	716,415
Current liabilities:
Accounts payable	28,032	17,805
Accrued expenses	9,419	4,783
Employee-related liabilities	51,556	34,159
Deferred revenue	10,182	6,082
Common stock warrants	147	14,261
Operating lease liabilities	9,279	9,421
Other current liabilities	23,241	17,341
Total current liabilities	131,856	103,852
Convertible senior notes, net - long-term	281,467	202,984
Operating lease liabilities - long-term	23,922	15,914
Other long-term liabilities	34,780	27,360
Total liabilities	472,025	350,110
Commitments and contingencies (Note 12)	0	0
Stockholders’ equity:
Common stock, $0.001 par value; 200,000 shares authorized, 63,833 and 62,335 shares issued and outstanding at December 31, 2021 and December 31, 2020, respectively.	64	62
Additional paid-in capital	1,068,259	1,025,233
Accumulated other comprehensive income (loss)	(616)	220
Accumulated deficit	(634,595)	(659,210)
Total stockholders’ equity	433,112	366,305
Total liabilities and stockholders’ equity	$ 905,137	$ 716,415