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Short-Term Investments
12 Months Ended
Dec. 31, 2021
Investments, Debt and Equity Securities [Abstract]  
Short-Term Investments Short-Term Investments
The Company invests in marketable securities primarily consisting of debt instruments of the U.S. Government, U.S. Government-sponsored enterprises, and financial institutions and corporations with strong credit ratings. The following represents a summary of the estimated fair value of short-term investments at December 31, 2021 and 2020 (in thousands):
At December 31, 2021Amortized
Cost
Gross Unrealized
Gain
Gross Unrealized
Loss
Estimated
Fair Value
Available-for-sale securities:
U.S. Treasury securities$222,206 $— $(482)$221,724 
Commercial paper218,391 14 (24)218,381 
Corporate debt securities58,881 — (45)58,836 
U.S. Government-sponsored enterprises50,773 (88)50,686 
Supranational bonds3,003 — — 3,003 
Total$553,254 $15 $(639)$552,630 

At December 31, 2020Amortized
Cost
Gross Unrealized
Gain
Gross Unrealized
Loss
Estimated
Fair Value
Available-for-sale securities:
U.S. Treasury securities$143,244 $12 $(2)$143,254 
Commercial paper108,892 (1)108,896 
Corporate debt securities85,788 48 (13)85,823 
U.S. Government-sponsored enterprises52,330 21 (1)52,350 
Total$390,254 $86 $(17)$390,323 
The contractual maturities of available-for-sale debt securities as of December 31, 2021, were as follows (in thousands):
Years to Maturity
At December 31, 2021Within One YearOne to Two YearsEstimated Fair Value
U.S. Treasury securities$105,231 $116,493 $221,724 
Commercial paper218,381 — 218,381 
Corporate debt securities58,836 — 58,836 
U.S. Government-sponsored enterprises32,282 18,404 50,686 
Supranational bonds3,003 — 3,003 
Total$417,733 $134,897 $552,630 

The Company has classified all marketable securities, regardless of maturity, as short-term investments based upon the Company’s ability and intent to use any of those marketable securities to satisfy the Company’s liquidity requirements.

The Company reviews the portfolio of available-for-sale debt securities quarterly to determine if any investment is impaired due to changes in credit risk or other potential valuation concerns. Unrealized losses on available-for-sale debt securities at December 31, 2021 were not significant and were primarily due to changes in market interest rates. The Company does not intend to sell the available-for-sale debt securities that are in an unrealized loss position, and it is not more likely than not that the Company will be required to sell these debt securities before recovery of their amortized cost bases, which may be at maturity. Based on the credit quality of the available-for-sale debt securities in an unrealized loss position, and the Company’s estimates of future cash flows to be collected from those securities, the Company believes the unrealized losses are not credit losses. Accordingly, the Company did not recognize any impairment losses related to its available-for-sale debt securities at December 31, 2021.