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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Beginning balance (shares) at Dec. 31, 2018   57,554,000      
Beginning balance at Dec. 31, 2018 $ 131,275 $ 57 $ 731,306 $ (13) $ (600,075)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Exercise of stock options (in shares)   409,000      
Exercise of stock options 1,899 $ 1 1,898    
Exercise of common stock warrants (shares)   19,000      
Exercise of common stock warrants 64   64    
Fair value of common stock warrants at time of exercise 910   910    
Stock-based compensation 9,752   9,752    
Unrealized gain on short-term investments 50     50  
Foreign currency translation gain (loss) 4     4  
Net loss (22,992)       (22,992)
Ending balance (shares) at Mar. 31, 2019   57,982,000      
Ending balance at Mar. 31, 2019 120,962 $ 58 743,930 41 (623,067)
Beginning balance (shares) at Dec. 31, 2019   59,396,000      
Beginning balance at Dec. 31, 2019 194,979 $ 59 819,626 122 (624,828)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Exercise of stock options (in shares)   673,000      
Exercise of stock options 11,475 $ 1 11,474    
Exercise of common stock warrants (shares)   2,000      
Exercise of common stock warrants 7   7    
Fair value of common stock warrants at time of exercise 141   141    
Stock-based compensation 15,808   15,808    
Unrealized gain on short-term investments 42     42  
Foreign currency translation gain (loss) (409)     (409)  
Net loss (14,867)       (14,867)
Ending balance (shares) at Mar. 31, 2020   60,071,000      
Ending balance at Mar. 31, 2020 $ 207,176 $ 60 $ 847,056 $ (245) $ (639,695)