Collaborative Arrangement, Milestones Payable

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- Definition

Lessee Leasing Arrangements, Operating Leases, Renewal Term, Option to Extend

+ References

No definition available.

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 360

-SubTopic 10

-Section 50

-Paragraph 1

-Subparagraph (c)

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Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 210

-SubTopic 10

-Section S99

-Paragraph 1

-Subparagraph (SX 210.5-02.14)

-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

Reference 3: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Regulation S-X (SX)

-Number 210

-Section 02

-Paragraph 14

-Article 5

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- Definition

Maximum potential amount of future payments (undiscounted) the guarantor could be required to make under the guarantee or each group of similar guarantees before reduction for potential recoveries under recourse or collateralization provisions.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 460

-SubTopic 10

-Section 50

-Paragraph 4

-Subparagraph (b)(1)

-URI http://asc.fasb.org/extlink&oid=6851643&loc=d3e12069-110248

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- Definition

Amount of rent expense incurred for leased assets, including but not limited to, furniture and equipment, that is not directly or indirectly associated with the manufacture, sale or creation of a product or product line.

+ References

No definition available.

+ Details

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Balance Type:	debit
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- Definition

Amount before accumulated depreciation of additions or improvements to assets held under a lease arrangement.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 360

-SubTopic 10

-Section 50

-Paragraph 1

-Subparagraph (b)

-URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229

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-Publisher FASB

-Name Accounting Standards Codification

-Topic 210

-SubTopic 10

-Section 45

-Paragraph 4

-Subparagraph (f)

-URI http://asc.fasb.org/extlink&oid=28358313&loc=d3e6812-107765

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- Definition

The total amount of the contingent obligation under letters of credit outstanding as of the reporting date.

+ References

No definition available.

+ Details

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- Definition

Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 360

-SubTopic 10

-Section 50

-Paragraph 1

-URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229

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-Publisher FASB

-Name Accounting Standards Codification

-Topic 210

-SubTopic 10

-Section S99

-Paragraph 1

-Subparagraph (SX 210.5-02.13)

-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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-Publisher SEC

-Name Regulation S-X (SX)

-Number 210

-Section 02

-Paragraph 13

-Subparagraph a

-Article 5

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-Publisher SEC

-Name Regulation S-X (SX)

-Number 210

-Section 03

-Paragraph 8

-Article 7

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Commitments and Contingencies - Narrative (Details) (USD $)	1 Months Ended	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Other Commitments [Line Items]
Property and equipment, net	$ 295,000us-gaap_PropertyPlantAndEquipmentNet	$ 401,000us-gaap_PropertyPlantAndEquipmentNet	$ 295,000us-gaap_PropertyPlantAndEquipmentNet
Leasehold Improvements, Gross	98,000us-gaap_LeaseholdImprovementsGross	37,000us-gaap_LeaseholdImprovementsGross	98,000us-gaap_LeaseholdImprovementsGross
Accumulated depreciation, leasehold improvements	1,972,000	2,203,000	1,972,000
Optional lease extension period	5 years
Funds drawn on letter of credit		0
Rent expense		576,000us-gaap_LeaseAndRentalExpense	561,000us-gaap_LeaseAndRentalExpense	325,000us-gaap_LeaseAndRentalExpense
Financial Standby Letter of Credit [Member]
Other Commitments [Line Items]
Letter of credit provided as security deposit	121,000		121,000
Collaborative Arrangement [Member] \| ZVex Product [Member]
Other Commitments [Line Items]
Potential future milestone payments		1,900,000
Collaborative Arrangement [Member] \| Infectious Disease Research Institute [Member] \| First GLA Product [Member]
Other Commitments [Line Items]
Potential future milestone payments		2,400,000
Collaborative Arrangement [Member] \| Infectious Disease Research Institute [Member] \| Subsequent GLA Products [Member]
Other Commitments [Line Items]
Potential future milestone payments		1,300,000
Leasehold improvements [Member]
Other Commitments [Line Items]
Property and equipment, net				448,000
Accumulated depreciation, leasehold improvements	$ 22,000	$ 50,000	$ 22,000