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Property and Equipment
12 Months Ended
Dec. 31, 2014
Property, Plant and Equipment [Abstract]  
Property and Equipment
Property and Equipment
Property and equipment consists of the following (in thousands):
 
 
DECEMBER 31,
 
 
2013
 
2014
 
 
 
 
 
Laboratory equipment
 
$
1,934

 
$
2,060

Leasehold improvements
 
98

 
135

Computer equipment and software
 
188

 
285

Office equipment, furniture, and fixtures
 
47

 
124

 
 
2,267

 
2,604

Less: accumulated depreciation and amortization
 
(1,972
)
 
(2,203
)
Total property and equipment, net
 
$
295

 
$
401


 
Depreciation and amortization expense was $548,000, $407,000 and $238,000 for the years ended December 31, 2012, 2013 and 2014, respectively.