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Property and Equipment
12 Months Ended
Dec. 31, 2017
Property, Plant and Equipment [Abstract]  
Property and Equipment
Property and Equipment
Property and equipment consists of the following (in thousands):
 
DECEMBER 31,
 
2017
 
2016
 
 
 
 
Laboratory equipment
$
2,624

 
$
2,330

Leasehold improvements
183

 
156

Computer equipment and software
584

 
483

Office equipment, furniture, and fixtures
178

 
174

Total
3,569

 
3,143

Less: accumulated depreciation and amortization
(3,078
)
 
(2,729
)
Total property and equipment, net
$
491

 
$
414



Depreciation and amortization expense was $351,000, $304,000 and $243,000 for the years ended December 31, 2017, 2016 and 2015, respectively.