X0306 4 2018-01-04 0 0001437786 Immune Design Corp. IMDZ 0001606241 Brady Stephen R C/O IMMUNE DESIGN CORP. 1616 EASTLAKE AVE. E., SUITE 310 SEATTLE WA 98102 0 1 0 0 EVP, Strategy & Finance Common Stock 2018-01-04 4 A 0 20000 0.00 A 50490 D Common Stock 2018-01-05 4 S 0 3328 4.1721 D 47162 D Stock Option (right to buy) 4.05 2018-01-04 4 A 0 100000 0.00 A 2028-01-04 Common Stock 100000 100000 D Each restricted stock unit represents a contingent right to receive one share of Immune Design Corp. common stock. Restricted stock units shall vest in a series of three equal consecutive annual installments beginning on January 4, 2019, subject to the Reporting Person's continuous service through each such date. The shares were sold pursuant to a Rule 10b5-1 trading plan that was included in the Reporting Person's restricted stock unit agreements, dated January 4, 2016 and January 4, 2017, in order to satisfy a tax liability incurred upon the vesting of restricted stock units on January 4, 2018. One quarter of the shares underlying the option will vest on January 4, 2019, and the remainder of the shares underlying the option will vest at a rate of 1/24th per month thereafter, subject to the Reporting Person's continuous service through each such date. /s/ Stephen R. Brady 2018-01-08