X0306 4 2017-01-04 0 0001437786 Immune Design Corp. IMDZ 0001606241 Brady Stephen R C/O IMMUNE DESIGN CORP. 1616 EASTLAKE AVE. E., SUITE 310 SEATTLE WA 98102 0 1 0 0 EVP, Strategy & Finance Common Stock 2017-01-04 4 A 0 15000 0.00 A 32132 D Common Stock 2017-01-04 4 S 0 1642 5.35 D 30490 D Stock Option (right to buy) 5.60 2017-01-04 4 A 0 85000 0.00 A 2027-01-04 Common Stock 85000 85000 D Each restricted stock unit represents a contingent right to receive one share of Immune Design Corp. common stock. One quarter of the total restricted stock units vest annually beginning January 4, 2018, subject to the Reporting Person's continuous service through each such date. The shares were sold pursuant to a Rule 10b5-1 trading plan that was included in the Reporting Person's restricted stock unit agreement, dated January 4, 2016, in order to satisfy a tax liability incurred upon the vesting of restricted stock units on January 4, 2017. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.25 to $5.42 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. One quarter of the shares underlying the option will vest on January 4, 2018, and the remainder of the shares underlying the option will vest at a rate of 1/36th per month thereafter, subject to the Reporting Person's continuous service through each such date. /s/ Stephen R. Brady 2017-01-06