X0306 4 2016-12-16 0 0001437786 Immune Design Corp. IMDZ 0001273885 BERGER FRANKLIN M C/O IMMUNE DESIGN CORP. 1616 EASTLAKE AVE. E., SUITE 310 SEATTLE WA 98102 1 0 0 0 Common Stock 2016-12-16 4 S 0 50000 6.5466 D 25000 D The price reported on Column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $6.35 to $6.90 on December 16, 2016. The reporting person will provide upon request to the SEC, the issuer or security holder of Issuer, full information regarding the number of shares sold at each separate price. /s/ Steven R. Brady, Attorney-In-Fact 2016-12-20