X0206 3 2019-05-08 0 0001408443 Milestone Pharmaceuticals Inc. MIST 0001437782 Oliveto Joseph C/O MILESTONE PHARMACEUTICALS INC. 1111 DR. FREDERIK-PHILIPS BLVD, STE 420 MONTR?AL A8 H4M 2X6 QUEBEC, CANADA 1 1 0 0 President and CEO Common Shares 273155 D Employee Stock Option (right to buy) 1.12 2026-09-19 Common Shares 121574 D Employee Stock Option (right to buy) 1.12 2027-01-03 Common Shares 8960 D Employee Stock Option (right to buy) 1.54 2027-12-12 Common Shares 121256 D Employee Stock Option (right to buy) 2.66 2028-10-25 Common Shares 191479 D Employee Stock Option (right to buy) 2.66 2028-11-20 Common Shares 263192 D The original grant was for 253,720 option shares. Twenty-five percent (25%) of the shares subject to the option vested on September 19, 2017, and one thirty-sixth (1/36th) of the remaining shares subject to the option vested or shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date. The original grant was for 18,375 option shares. Twenty-five percent (25%) of the shares subject to the option vested on September 19, 2017, and one thirty-sixth (1/36th) of the remaining shares subject to the option vested or shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date. The original grant was for 252,853 option shares. Twenty-five percent (25%) of the shares subject to the option vested on September 19, 2017, and one thirty-sixth (1/36th) of the remaining shares subject to the option vested or shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date. Twenty-five percent (25%) of the shares subject to the option vested on September 19, 2017, and one thirty-sixth (1/36th) of the remaining shares subject to the option vested or shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date. Twenty-five percent (25%) of the shares subject to the option shall vest on November 21, 2019, and one thirty-sixth (1/36th) of the remaining shares subject to the option shall vest each month thereafter, subject to the Reporting Person continuing to provide service through each such date. Exhibit List - Exhibit 24 - Power of Attorney /s/ Eric Popp, Attorney-in-Fact 2019-05-08