144 0001611311 XXXXXXXX LIVE 0001437402 ARDELYX, INC. 001-36485 400 FIFTH AVE., SUITE 210 WALTHAM, MA 02451 510-745-7047 Rosenbaum David P. Officer COMMON MORGAN STANLEY SMITH BARNEY LLC EXECUTIVE SERVICES

200 W CIVIC CENTER DR - 4TH FLOOR SANDY UT 84070

44330 242558.62 238400000 03/17/2025 NASDAQ COMMON 01/01/2022 RESTRICTED STOCK ISSUER N 22150 01/01/2022 COMPENSATION COMMON 01/01/2023 RESTRICTED STOCK ISSUER N 12393 01/01/2023 COMPENSATION COMMON 01/01/2024 RESTRICTED STOCK ISSUER N 7438 01/01/2024 COMPENSATION COMMON 02/29/2024 ESPP ISSUER N 2349 02/29/2024 COMPENSATION N DAVID P ROSENBAUM

400 FIFTH AVE SUITE 210 WALTHAM MA 02451

RESTRICTED STOCK 02/20/2025 4816 27080.20 Table 1 Breakdown: 15,996 6/1/2022 3,080 8/19/2022 3,074 11/19/2022 2,898 8/19/2023 3,166 5/19/2023 3,162 8/19/2023 3,167 11/19/2023 3,155 2/19/2024 1,436 5/19/2024 1,423 8/19/2024 1,424 11/19/2024 03/17/2025 /s/ David Paul Rosenbaum