144 0001815433 XXXXXXXX LIVE 0001437402 ARDELYX, INC. 001-36485 400 FIFTH AVE. SUITE 210 WALTHAM MA 02451 510-745-7047 Blanks Robert Officer COMMON MORGAN STANLEY SMITH BARNEY LLC EXECUTIVE SERVICES

200 W CIVIC CENTER DR - 4TH FLOOR SANDY UT 84070

75000 409765.20 236900000 02/12/2025 NASDAQ COMMON 02/12/2025 STOCK OPTION EXERCISE ISSUER N 75000 02/12/2025 COMPENSATION N ROBERT C BLANKS

400 FIFTH AVE., SUITE 210, WALTHAM MA 02451

RESTRICTED STOCK 11/20/2024 4941 23689.52 02/12/2025 /s/ Robert Christian Blanks