STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Operating activities
Net loss	$ (39,136)	$ (66,067)	$ (67,207)
Adjustments to reconcile net loss to net cash used in operating activities
Depreciation and amortization expense	2,063	1,292	1,144
Non-cash lease expense	4,008	3,624	3,457
Stock-based compensation	37,381	13,530	10,750
Non-cash interest expense	7,400	4,220	1,962
Non-cash royalty revenue related to the sale of future royalties	(2,692)	0	0
Gain on sale of equipment	0	0	(1,260)
Other, net	(4,664)	(2,930)	685
Changes in operating assets and liabilities
Accounts receivable	(35,674)	(14,298)	(7,231)
Inventory	(41,697)	(21,141)	(28,346)
Prepaid commercial manufacturing	6,782	(9,593)	(4,161)
Prepaid expenses and other assets	(4,543)	(6,035)	2,299
Accounts payable	4,862	279	6,582
Accrued compensation and benefits	2,343	5,049	2,126
Operating lease liabilities	(4,588)	(3,928)	(3,491)
Accrued and other liabilities	21,254	3,691	4,138
Deferred revenue	2,092	2,590	8,509
Net cash used in operating activities	(44,809)	(89,717)	(70,044)
Investing activities
Proceeds from maturities and redemptions of investments	177,854	84,321	67,000
Purchases of investments	(195,161)	(215,225)	(50,328)
Proceeds from sale of property and equipment	0	0	1,798
Purchases of property and equipment	(1,011)	(344)	(55)
Net cash (used in) provided by investing activities	(18,318)	(131,248)	18,415
Financing activities
Proceeds from issuance of common stock in at the market offering, net of issuance costs	0	119,236	71,625
Proceeds from 2022 Loan Agreement, net of issuance costs	99,451	22,386	26,971
Proceeds from the sale of future royalties, net of issuance costs	0	5,000	9,581
Proceeds from issuance of common stock under equity incentive and stock purchase plans	8,138	1,173	202
Payment of the exit fees	(1,000)	(1,500)	0
Payments for the 2018 Loan, net of costs	0	0	(33,038)
Net cash provided by financing activities	106,589	146,295	75,341
Net increase (decrease) in cash and cash equivalents	43,462	(74,670)	23,712
Cash and cash equivalents at beginning of period	21,470	96,140	72,428
Cash and cash equivalents at end of period	64,932	21,470	96,140
Supplementary disclosure of cash flow information
Cash paid for interest	11,408	4,240	2,901
Cash paid for income taxes	266	51	6
Supplementary disclosure of non-cash activities
Right-of-use assets obtained in exchange for lease obligations	1,010	339	0
Issuance of common stock for services	257	337	390
Issuance of derivative in connection with issuance of loan payable	$ 0	$ 0	$ 375