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CONDENSED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Income
Beginning balance (in shares) at Dec. 31, 2021   130,182,535      
Beginning balance at Dec. 31, 2021 $ 82,617 $ 13 $ 795,540 $ (712,930) $ (6)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   127,100      
Issuance of common stock under employee stock purchase plan 83   83    
Issuance of common stock upon vesting of restricted stock units (in shares)   2,996,142      
Issuance of common stock in at the market offering (in shares)   20,492,057      
Issuance of common stock in at the market offering 18,478 $ 2 18,476    
Stock-based compensation 6,976   6,976    
Unrealized losses on available-for-sale securities (103)       (103)
Net loss (55,009)     (55,009)  
Ending balance (in shares) at Jun. 30, 2022   153,797,834      
Ending balance at Jun. 30, 2022 53,042 $ 15 821,075 (767,939) (109)
Beginning balance (in shares) at Mar. 31, 2022   136,330,360      
Beginning balance at Mar. 31, 2022 64,190 $ 14 805,265 (741,001) (88)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon vesting of restricted stock units (in shares)   2,882,673      
Issuance of common stock in at the market offering (in shares)   14,584,801      
Issuance of common stock in at the market offering 12,557 $ 1 12,556    
Stock-based compensation 3,254   3,254    
Unrealized losses on available-for-sale securities (21)       (21)
Net loss (26,938)     (26,938)  
Ending balance (in shares) at Jun. 30, 2022   153,797,834      
Ending balance at Jun. 30, 2022 53,042 $ 15 821,075 (767,939) (109)
Beginning balance (in shares) at Dec. 31, 2022   198,575,016      
Beginning balance at Dec. 31, 2022 98,329 $ 20 878,500 (780,137) (54)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   165,969      
Issuance of common stock under employee stock purchase plan 138   138    
Issuance of common stock for services (in shares)   86,095      
Issuance of common stock for services $ 337   337    
Issuance of common stock upon exercise of options (in shares) 99,000 98,994      
Issuance of common stock upon exercise of options $ 211   211    
Issuance of common stock upon vesting of restricted stock units (in shares)   423,074      
Issuance of common stock in at the market offering (in shares)   18,513,773      
Issuance of common stock in at the market offering 62,085 $ 2 62,083    
Stock-based compensation 6,111   6,111    
Unrealized losses on available-for-sale securities (156)       (156)
Net loss (43,894)     (43,894)  
Ending balance (in shares) at Jun. 30, 2023   217,862,921      
Ending balance at Jun. 30, 2023 123,161 $ 22 947,380 (824,031) (210)
Beginning balance (in shares) at Mar. 31, 2023   214,462,050      
Beginning balance at Mar. 31, 2023 125,421 $ 21 932,330 (806,910) (20)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock for services (in shares)   86,095      
Issuance of common stock for services 337   337    
Issuance of common stock upon exercise of options (in shares)   62,993      
Issuance of common stock upon exercise of options 149   149    
Issuance of common stock upon vesting of restricted stock units (in shares)   215,301      
Issuance of common stock in at the market offering (in shares)   3,036,482      
Issuance of common stock in at the market offering 11,366 $ 1 11,365    
Stock-based compensation 3,199   3,199    
Unrealized losses on available-for-sale securities (190)       (190)
Net loss (17,121)     (17,121)  
Ending balance (in shares) at Jun. 30, 2023   217,862,921      
Ending balance at Jun. 30, 2023 $ 123,161 $ 22 $ 947,380 $ (824,031) $ (210)