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CONDENSED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Income
Beginning balance (in shares) at Dec. 31, 2021   130,182,535      
Beginning balance at Dec. 31, 2021 $ 82,617 $ 13 $ 795,540 $ (712,930) $ (6)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   127,100      
Issuance of common stock under employee stock purchase plan 83   83    
Issuance of common stock upon vesting of restricted stock units (in shares)   113,469      
Issuance of common stock in at the market offering (in shares)   5,907,256      
Issuance of common stock in at the market offering 5,921 $ 1 5,920    
Stock-based compensation 3,722   3,722    
Unrealized gains (losses) on available-for-sale securities (82)       (82)
Net loss (28,071)     (28,071)  
Ending balance (in shares) at Mar. 31, 2022   136,330,360      
Ending balance at Mar. 31, 2022 64,190 $ 14 805,265 (741,001) (88)
Beginning balance (in shares) at Dec. 31, 2022   198,575,016      
Beginning balance at Dec. 31, 2022 98,329 $ 20 878,500 (780,137) (54)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   165,969      
Issuance of common stock under employee stock purchase plan $ 138   138    
Issuance of common stock upon exercise of options (in shares) 36,000 36,001      
Issuance of common stock upon exercise of options $ 62   62    
Issuance of common stock upon vesting of restricted stock units (in shares)   207,773      
Issuance of common stock in at the market offering (in shares)   15,477,291      
Issuance of common stock in at the market offering 50,719 $ 1 50,718    
Stock-based compensation 2,912   2,912    
Unrealized gains (losses) on available-for-sale securities 34       34
Net loss (26,773)     (26,773)  
Ending balance (in shares) at Mar. 31, 2023   214,462,050      
Ending balance at Mar. 31, 2023 $ 125,421 $ 21 $ 932,330 $ (806,910) $ (20)