Accrued Expenses and Other Current Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Accrued payments due to AstraZeneca	$ 3,385	$ 69
Accrued gross to net revenue liabilities	1,991	0
Accrued contract manufacturing expenses	1,657	2,485
Derivative liability for exit fees	1,656	698
Accrued non-clinical research and development expenses	1,188	265
Accrued professional and consulting services	808	597
Accrued sales and marketing expenses	587	256
Accrued clinical expenses	223	2,522
Other	885	474
Total accrued expenses and other current liabilities	$ 12,380	$ 7,366