STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenues:
Total revenues	$ 52,158,000	$ 10,097,000	$ 7,571,000
Operating expenses:
Cost of revenue	4,117,000	1,000,000	145,000
Research and development	35,201,000	91,140,000	65,053,000
Selling, general and administrative	76,599,000	72,303,000	33,153,000
Total operating expenses	115,917,000	164,443,000	98,351,000
Loss from operations	(63,759,000)	(154,346,000)	(90,780,000)
Interest expense	(3,400,000)	(4,502,000)	(5,099,000)
Non-cash interest expense related to the sale of future royalties	(1,673,000)	0	0
Other income, net	1,633,000	687,000	1,568,000
Loss before provision for income taxes	(67,199,000)	(158,161,000)	(94,311,000)
Provision for income taxes	8,000	4,000	2,000
Net loss	$ (67,207,000)	$ (158,165,000)	$ (94,313,000)
Net loss per share of common stock - basic (in dollars per share)	$ (0.42)	$ (1.52)	$ (1.05)
Net loss per share of common stock - diluted (in dollars per share)	$ (0.42)	$ (1.52)	$ (1.05)
Shares used in computing net loss per share - basic	158,690,083	104,205,645	89,582,138
Shares used in computing net loss per share - diluted	158,690,083	104,205,645	89,582,138
Comprehensive loss:
Net loss	$ (67,207,000)	$ (158,165,000)	$ (94,313,000)
Unrealized losses on available-for-sale securities	(48,000)	(2,000)	(24,000)
Comprehensive loss	(67,255,000)	(158,167,000)	(94,337,000)
Product sales, net
Revenues:
Total revenues	15,600,000	0	0
Product supply revenue
Revenues:
Total revenues	1,527,000	907,000	1,501,000
Licensing revenue
Revenues:
Total revenues	35,031,000	5,013,000	706,000
Collaborative development revenue
Revenues:
Total revenues	$ 0	$ 4,177,000	$ 5,364,000