CONDENSED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 53,408	$ 72,428
Short-term investments	27,604	44,261
Accounts receivable	5,623	502
Inventory	4,529	0
Prepaid commercial manufacturing	17,793	9,406
Prepaid expenses and other current assets	5,150	7,052
Total current assets	114,107	133,649
Right-of-use assets	11,054	12,752
Property and equipment, net	1,541	2,362
Other assets	4,908	1,150
Total assets	131,610	149,913
Current liabilities:
Accounts payable	4,294	4,277
Accrued compensation and benefits	6,405	5,422
Current portion of long-term debt	26,373	32,264
Current portion of operating lease liability	3,691	3,492
Accrued expenses and other current liabilities	7,936	7,366
Total current liabilities	48,699	52,821
Operating lease liability, net of current portion	7,857	9,748
Deferred revenue, non-current	12,421	4,727
Deferred royalty obligation	9,591	0
Total liabilities	78,568	67,296
Commitments and contingencies (Note 14)
Stockholders’ equity:
Preferred stock, $0.0001 par value; 5,000,000 shares authorized; no shares issued and outstanding as of June 30, 2022 and December 31, 2021, respectively.	0	0
Common stock, $0.0001 par value; 300,000,000 shares authorized; 153,797,834 and 130,182,535 shares issued and outstanding as of June 30, 2022 and December 31, 2021, respectively.	15	13
Additional paid-in capital	821,075	795,540
Accumulated deficit	(767,939)	(712,930)
Accumulated other comprehensive loss	(109)	(6)
Total stockholders’ equity	53,042	82,617
Total liabilities and stockholders’ equity	$ 131,610	$ 149,913