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Stockholders' Equity (Details) - USD ($)
$ / shares in Units, shares in Millions
1 Months Ended 3 Months Ended
Apr. 27, 2022
Mar. 31, 2022
Mar. 31, 2021
Aug. 31, 2021
Jul. 31, 2020
Subsidiary, Sale of Stock [Line Items]          
Proceeds from issuance of common stock in at the market offering, net of issuance costs   $ 5,921,000 $ 34,272,000    
Common stock          
Subsidiary, Sale of Stock [Line Items]          
Maximum aggregate offering price         $ 250,000,000
2020 Open Market Sales Agreement          
Subsidiary, Sale of Stock [Line Items]          
Issuance of common stock in at the market offering (shares)     4.9    
Proceeds from issuance of common stock in at the market offering, net of issuance costs     $ 35,000,000    
Weighted-average sales price per share     $ 7.09    
2020 Open Market Sales Agreement | Common stock          
Subsidiary, Sale of Stock [Line Items]          
Maximum aggregate offering price         $ 100,000,000
2021 Open Market Sales Agreement          
Subsidiary, Sale of Stock [Line Items]          
Commission on sale of stock per agreement (percent)   3.00%      
Issuance of common stock in at the market offering (shares)   5.9      
Proceeds from issuance of common stock in at the market offering, net of issuance costs   $ 6,000,000      
Weighted-average sales price per share   $ 1.02      
2021 Open Market Sales Agreement | Common stock          
Subsidiary, Sale of Stock [Line Items]          
Maximum aggregate offering price       $ 150,000,000  
2021 Open Market Sales Agreement | Subsequent event          
Subsidiary, Sale of Stock [Line Items]          
Issuance of common stock in at the market offering (shares) 8.3        
Proceeds from issuance of common stock in at the market offering, net of issuance costs $ 9,000,000        
Weighted-average sales price per share $ 1.09