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Collaboration and Licensing Agreements - Additional Information (Details) (USD $)
In Millions, unless otherwise specified
1 Months Ended 3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 1 Months Ended
May 31, 2014
AstraZeneca
Dec. 31, 2013
AstraZeneca
Oct. 31, 2012
AstraZeneca
Jun. 30, 2014
AstraZeneca
Jun. 30, 2014
AstraZeneca
Future Development Milestones
Jun. 30, 2014
AstraZeneca
Launch, Commercialization, and Sales Milestones
Jun. 30, 2014
AstraZeneca
Amortization of Up-Front and Other License Fees
Jun. 30, 2013
AstraZeneca
Amortization of Up-Front and Other License Fees
Jun. 30, 2014
AstraZeneca
Amortization of Up-Front and Other License Fees
Jun. 30, 2013
AstraZeneca
Amortization of Up-Front and Other License Fees
Jun. 30, 2014
AstraZeneca
Collaborative Development Services
Jun. 30, 2013
AstraZeneca
Collaborative Development Services
Jun. 30, 2014
AstraZeneca
Collaborative Development Services
Jun. 30, 2013
AstraZeneca
Collaborative Development Services
May 31, 2014
Sanofi
Jun. 30, 2014
Sanofi
Revenue Recognition Multiple Deliverable Arrangements [Line Items]                                
Deferred Revenue, Additions $ 25.0 $ 15.0 $ 35.0                          
Future potential payments to be recieved       795.0 197.5 597.5                   196.8
Revenue recognized             6.50 2.00 9.70 4.00 2.60 5.30 7.90 9.90 1.25  
Deferred revenue   $ 40.3   $ 56.4