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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Operating activities    
Net loss $ (47,329) $ (51,611)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 960 1,353
Amortization of deferred financing costs 282 282
Amortization of deferred compensation for services 158 154
Amortization of premium on investment securities (227) (537)
Non-cash lease expense 1,025 891
Stock-based compensation 5,622 3,845
Change in derivative liabilities 152 61
Non-cash interest associated with debt discount accretion 257 231
Changes in operating assets and liabilities:    
Unbilled revenue   5,000
Prepaid expenses and other assets (2,144) 12
Accounts payable 2,025 (887)
Accrued compensation and benefits (1,372) (372)
Lease liabilities (1,251) (825)
Accrued and other liabilities 174 (2,330)
Deferred revenue (2,300)  
Net cash used in operating activities (43,968) (44,733)
Investing activities    
Proceeds from maturities of investments 25,519 86,454
Purchases of investments (62,960) (30,857)
Purchases of property and equipment (25) (211)
Net cash (used in) provided by investing activities (37,466) 55,386
Financing activities    
Proceeds from issuance of common stock under stock plans 375 198
Issuance of common stock upon exercise of options 420 7
Net cash provided by financing activities 795 205
Net (decrease) increase in cash and cash equivalents (80,639) 10,858
Cash and cash equivalents at beginning of period 181,133 78,768
Cash and cash equivalents at end of period $ 100,494 89,626
Supplementary disclosure of cash flow information:    
Income taxes paid   2
Supplementary disclosure of non-cash activities:    
Right-of-use assets obtained in exchange for lease obligations   $ 5,810