Selected Quarterly Financial Data (Unaudited) - Schedule of Selected Quarterly Financial Results from Operations (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	12 Months Ended
Dec. 31, 2019	Sep. 30, 2019	Jun. 30, 2019	Mar. 31, 2019	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Selected Quarterly Financial Data (Unaudited)
Total revenue	$ 2,250	$ 3,013	$ 18		$ 85	$ 172	$ 30	$ 2,320	$ 5,281	$ 2,607	$ 42,000
Gross profit	2,250	2,413	18		85	170	30	1,856	4,681	2,141	33,600
Operating expenses	21,098	24,502	24,846	$ 25,498	27,461	23,902	22,184	19,541	95,944	93,088	98,715
Net loss	$ (19,790)	$ (23,539)	$ (25,467)	$ (26,144)	$ (27,862)	$ (24,126)	$ (22,291)	$ (17,019)	$ (94,940)	$ (91,298)	$ (64,339)
Net (loss) income per share:
Net loss per share - basic and diluted	$ (0.27)	$ (0.37)	$ (0.41)	$ (0.42)	$ (0.45)	$ (0.39)	$ (0.42)	$ (0.36)	$ (1.47)	$ (1.62)	$ (1.36)

The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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