Selected Quarterly Financial Data (Unaudited) (Tables)

12 Months Ended

Dec. 31, 2017

Quarterly Financial Information Disclosure [Abstract]

Schedule of Selected Quarterly Financial Results from Operations

Selected quarterly financial results from operations for the years ended December 31, 2017 and 2016 are as follows (in thousands, except per share amounts):

	2017 Quarter End
	March 31		June 30		September 30		December 31
Total revenue	$	—	$	—	$	—	$	42,000
Gross profit		—		—		—		33,600
Operating expenses		28,434		26,418		21,225		22,638
Net income (loss)		(28,008)		(25,721)		(20,724)		10,114
Net income (loss) per share - basic	$	(0.59)	$	(0.54)	$	(0.44)	$	0.21
Net income (loss) per share - diluted	$	(0.59)	$	(0.54)	$	(0.44)	$	0.21

	2016 Quarter End
	March 31		June 30		September 30		December 31
Total revenue	$	—	$	—	$	—	$	—
Operating expenses		23,529		28,690		29,200		31,476
Net loss		(23,467)		(28,613)		(29,031)		(31,276)
Net loss per share - basic and diluted	$	(0.70)	$	(0.83)	$	(0.65)	$	(0.66)