X0306 4 2016-01-15 0 0001437402 ARDELYX, INC. ARDX 0001611184 Kaufmann Mark C/O ARDELYX, INC. 34175 ARDENWOOD BLVD, SUITE 200 FREMONT CA 94555 0 1 0 0 Chief Financial Officer Common Stock 2015-08-31 4 A 0 686 13.991 A 1282 D Stock Option (Right to Buy) 10.55 2016-01-15 4 A 0 102701 0.00 A 2026-01-15 Common Stock 102701 102701 D The shares were acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2015. The option becomes exercisable as it vests and the shares subject to the option vest in 48 successive, equal monthly installments on each monthly anniversary of January 15, 2016, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date. /s/ Elizabeth Grammer, Attorney-in-Fact for Mark Kaufmann 2016-01-20