X0303 4/A 2008-07-15 2008-07-17 0 0000732485 GENZYME CORP GENZ 0001435745 Bamforth Mark R GENZYME CORPORATION 500 KENDALL STREET CAMBRIDGE MA 02142 0 1 0 0 Sr.VP, Corp. Operations & Phar Genzyme NQ stock option (right to buy) 32.52 2008-07-15 4 J 0 6445 32.52 A 2002-05-30 2012-05-30 Genzyme common stock (GENZ) 6445 6445 D On July 17, 2008 reporting person filed a Form 4 for the exercise of an option and sale of shares under a 10b5-1 plan that did not meet the requirements of the plan, and the transaction was reversed. The exercise of the option was originally reported as an acquisition. By: Susan P. Cogswell, Attorney-in-Fact 2008-07-17