Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Cash Flows from Operating Activities
Net loss	$ (31,684)	$ (37,215)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization expense	866	804
Loss on disposal of property and equipment	234
Amortization of intangible assets	429	420
Non-cash operating lease expense	1,528	1,291
Stock-based compensation expense	4,269	2,478
Change in fair value of contingent consideration and contingent value rights liabilities	(1,038)	1,839
Accretion of discounts and amortization of premiums on marketable securities	406
Share of net loss of equity method investment	775
Changes in operating assets and liabilities:
Accounts receivable	7,114	6
Prepaid expenses and other assets	(3,155)	(9)
Accounts payable	745	3,814
Accrued and other liabilities	(4,191)	(720)
Operating lease liabilities	(1,020)	(694)
Deferred revenue		(95)
Net cash used in operating activities	(24,722)	(28,081)
Cash Flows from Investing Activities
Purchases of marketable securities	(79,033)	(33,657)
Proceeds from marketable securities	23,834	41,818
Purchases of property and equipment	(374)	(594)
Proceeds from sale of property and equipment		267
Net cash provided by (used in) investing activities	(55,573)	7,834
Cash Flows from Financing Activities
Proceeds from exercise of stock options and warrants	2,049	580
Previously incurred issuance costs related to an underwritten public offering paid during period	(286)
Net cash provided by financing activities	1,763	580
Effect of exchange rate changes on cash, cash equivalents and restricted cash	308	9
Net decrease in cash, cash equivalents and restricted cash	(78,224)	(19,658)
Cash, cash equivalents and restricted cash at beginning of period	183,798	189,500
Cash, cash equivalents and restricted cash at end of period	105,574	169,842
Reconciliation of Cash, Cash Equivalents and Restricted Cash
Cash and cash equivalents	103,500	168,092
Restricted cash	2,074	1,750
Total cash, cash equivalents and restricted cash	105,574	169,842
Supplemental Cash Flow Information
Cash paid for amounts included in the measurement of lease liabilities	1,861	1,423
Supplemental Disclosure of Non-Cash Investing and Financing Activities
Purchases of property and equipment included in accounts payable and in accrued and other current liabilities	157	$ 76
Receivable from option exercises	$ 1,325