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Consolidated Statement of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash Flows from Operating Activities    
Net loss $ (102,937) $ (81,622)
Adjustments to reconcile net loss to net cash used in operating activities:    
Reversal of non-cash consideration related to revenue (41,200)  
Depreciation and amortization expense 3,065 992
Amortization of finance lease right-of-use asset   22
Amortization of intangible assets 1,687 422
Gain on disposal of property and equipment   (44)
Non-cash operating lease expense 5,688 1,486
Stock-based compensation expense 12,785 3,611
Change in fair value of redeemable convertible preferred stock tranche liability   27,696
Change in fair value of contingent consideration and contingent value rights liabilities 27,317 1,510
Accretion of discounts and amortization of premiums on marketable securities 211 4
Financial advisory expenses paid through issuance of common stock   500
Deferred income taxes 2,093 (2,003)
Gain on sale of assets to equity method investment (7,227)  
Share of net loss of equity method investment 1,636 0
Changes in operating assets and liabilities:    
Accounts receivable (9,799) 818
Prepaid expenses and other assets 675 (7,980)
Accounts payable 4,547 553
Accrued and other liabilities 1,972 (825)
Operating lease liabilities (3,162) (423)
Deferred revenue (95) (565)
Net cash used in operating activities (102,744) (55,848)
Cash Flows from Investing Activities    
Cash, cash equivalents and restricted cash acquired in connection with the Merger   74,909
Purchases of marketable securities (232,343) (16,590)
Proceeds from marketable securities 121,315 52,000
Purchases of property and equipment (1,878) (797)
Proceeds from sale of property and equipment 267 150
Net cash provided by (used in) investing activities (112,639) 109,672
Cash Flows from Financing Activities    
Proceeds from issuance of common stock pursuant to subscription agreements prior to Merger, net of offering costs   109,414
Proceeds from issuance of common stock and accompanying pre-funded warrants in underwritten public offering, net of issuance costs 172,527  
Proceeds from exercise of stock options and warrants and from employee stock purchase plan 3,106 446
Proceeds from at-the-market-sales agreement, net of issuance costs 33,891  
Proceeds from issuance of redeemable convertible preferred stock and related tranche rights, net of issuance costs   14,479
Repayment of finance lease liability   (47)
Net cash provided by financing activities 209,524 124,292
Effect of exchange rate changes on cash, cash equivalents and restricted cash 157 27
Net increase (decrease) in cash, cash equivalents and restricted cash (5,702) 178,143
Cash, cash equivalents and restricted cash at beginning of period 189,500 11,357
Cash, cash equivalents and restricted cash at end of period 183,798 189,500
Reconciliation of Cash, Cash Equivalents and Restricted Cash    
Cash and cash equivalents 181,724 187,750
Restricted cash 2,074 1,750
Total cash, cash equivalents and restricted cash 183,798 189,500
Supplemental Cash Flow Information    
Cash paid for amounts included in the measurement of lease liabilities 6,270 1,321
Supplemental Disclosure of Non-Cash Investing and Financing Activities    
Purchases of property and equipment included in accounts payable and in accrued and other current liabilities 174 425
Right-of-use asset for office space acquired through leases 5,406 1,449
Issuance costs incurred but unpaid 286  
Investment in equity securities acquired through non-cash consideration $ 41,200  
Fair value of net assets acquired in Merger   185,992
Conversion of redeemable convertible stock to common stock upon closing of the Merger   44,037
Financial advisory expenses paid through issuance of common stock   500
Termination of redeemable convertible preferred stock tranche liability   $ 9,723