Consolidated Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($) shares in Thousands, $ in Thousands	Total	Redeemable Convertible Preferred Stock	Common Stock	Additional Paid-In Capital	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)
Beginning balance at Dec. 31, 2019	$ (41,119)			$ 6,095	$ (47,207)	$ (7)
Beginning balance, Shares at Dec. 31, 2019		7,597
Beginning balance at Dec. 31, 2019		$ 19,835
Beginning balance, Shares at Dec. 31, 2019			4,502
Issuance of common stock upon exercise of stock options, issuance of common stock under Employee Stock Purchase Plan, and vesting of restricted stock units	446			446
Issuance of common stock upon exercise of stock options issuance of common stock under employee stock purchase plan and vesting of restricted stock units, shares			94
Repurchase of unvested restricted stock awards			(72)
Issuance of Series A redeemable convertible preferred stock, net of issuance costs		$ 14,479
Issuance of Series A redeemable, Shares		4,237
Reclassification of redeemable convertible preferred stock tranche liability upon exercise, Value		$ 9,723
Conversion of redeemable convertible preferred stock to common stock, Value	44,037		$ 1	44,036
Conversion of redeemable convertible preferred stock to common stock, shares		(11,834)
Conversion of redeemable convertible preferred stock to common stock		$ (44,037)
Conversion of redeemable convertible preferred stock to common stock, shares			11,834
Reclassification of redeemable preferred stock tranche liability to additional paid-in capital upon termination of rights, Value	50,706			50,706
Issuance of common stock pursuant to subscription agreements prior to Merger, Value	109,414		$ 1	109,413
Issuance of common stock pursuant to subscription agreements prior to Merger, shares			9,583
Aduro outstanding common stock assumed as a result of the Merger, Value	248,631		$ 2	248,629
Aduro outstanding common stock assumed as a result of the Merger, shares			16,307
Issuance of common stock for financial advisory services in connection with the Merger, Value	500			500
Issuance of common stock for financial advisory services in connection with the Merger, Shares			34
Stock-based compensation expense	3,611			3,611
Other comprehensive gain (loss)	18					18
Net loss	(81,622)				(81,622)
Ending balance at Dec. 31, 2020	$ 334,622		$ 4	463,436	(128,829)	11
Ending balance, Shares at Dec. 31, 2020	42,282		42,282
Issuance of common stock upon exercise of stock options, issuance of common stock under Employee Stock Purchase Plan, and vesting of restricted stock units	$ 3,106			3,106
Issuance of common stock upon exercise of stock options issuance of common stock under employee stock purchase plan and vesting of restricted stock units, shares			724
Issuance of common stock under the at-the-market sales agreement, net of issuance costs	33,891			33,891
Issuance of common stock under the at-the-market sales agreement net of offering costs, shares			2,216
Issuance of common stock and accompanying pre funded warrants in underwritten public offering, net of issuance costs	172,242		$ 1	172,241
Issuance of common stock and accompanying pre funded warrants in underwritten public offering, net of issuance costs, shares			9,539
Stock-based compensation expense	12,785			12,785
Other comprehensive gain (loss)	(66)					(66)
Net loss	(102,937)				(102,937)
Ending balance at Dec. 31, 2021	$ 453,643		$ 5	$ 685,459	$ (231,766)	$ (55)
Ending balance, Shares at Dec. 31, 2021	54,761		54,761