Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Sep. 30, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 120,751	$ 157,614
Short-term marketable securities	145,043	168,489
Accounts receivable		989
Income tax receivable	17,841	17,495
Prepaid expenses and other current assets	4,128	5,544
Total current assets	287,763	350,131
Long-term marketable securities	12,840	23,614
Property and equipment, net	29,806	31,085
Goodwill	8,449	8,723
Intangible assets, net	29,698	31,107
Restricted cash	468	468
Total assets	369,024	445,128
Current liabilities:
Accounts payable	780	1,150
Accrued clinical trial and manufacturing expenses	3,760	5,898
Accrued expenses and other liabilities	8,601	12,601
Contingent consideration		6,829
Deferred revenue	17,744	14,923
Total current liabilities	30,885	41,401
Deferred rent	10,843	9,991
Contingent consideration	941	759
Deferred revenue	161,591	148,148
Deferred tax liabilities	6,237	6,538
Other long-term liabilities	832	818
Total liabilities	211,329	207,655
Commitments and contingencies (Note 7)
Stockholders’ equity:
Preferred stock, $0.0001 par value; 10,000,000 shares authorized; and no shares issued and outstanding at September 30, 2018 and December 31, 2017
Common stock, $0.0001 par value; 300,000,000 shares authorized; and 79,369,891 and 77,736,201 shares issued and outstanding at September 30, 2018 and December 31, 2017	8	8
Additional paid-in capital	534,632	519,435
Accumulated other comprehensive income	1,267	1,893
Accumulated deficit	(378,212)	(283,863)
Total stockholders’ equity	157,695	237,473
Total liabilities and stockholders’ equity	$ 369,024	$ 445,128