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Condensed Consolidated Statements of Operations (Unaudited) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Revenue:        
Collaboration and license revenue $ 3,794,000 $ 18,720,000 $ 46,715,000 $ 37,581,000
Grant revenue   426,000 88,000 1,022,000
Total revenue 3,794,000 19,146,000 46,803,000 38,603,000
Operating expenses:        
Research and development 19,046,000 11,813,000 66,855,000 35,992,000
General and administrative 8,556,000 6,908,000 26,255,000 19,000,000
Amortization of intangible assets 138,000 0 415,000 0
Total operating expenses 27,740,000 18,721,000 93,525,000 54,992,000
Income (loss) from operations (23,946,000) 425,000 (46,722,000) (16,389,000)
Loss from remeasurement of fair value of warrants       (26,077,000)
Interest income, net 566,000 139,000 1,540,000 156,000
Other (loss) income, net (1,000) 3,000 (32,000) 1,000
Income (loss) before income tax (23,381,000) 567,000 (45,214,000) (42,309,000)
Provision for income taxes 11,670,000 0 16,368,000 0
Net income (loss) $ (35,051,000) $ 567,000 $ (61,582,000) $ (42,309,000)
Net income (loss) per common share, basic $ (0.54) $ 0.01 $ (0.96) $ (1.09)
Net income (loss) per common share, diluted $ (0.54) $ 0.01 $ (0.96) $ (1.09)
Shares used in computing net loss per common share, basic 65,134,102 62,274,438 64,472,947 38,674,889
Shares used in computing net loss per common share, diluted 65,134,102 71,726,118 64,472,947 38,674,889