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Condensed Consolidated Statements of Operations (Unaudited) - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Revenue:    
Collaboration and license revenue $ 3,983,000 $ 9,238,000
Grant revenue 47,000 336,000
Total revenue 4,030,000 9,574,000
Operating expenses:    
Research and development 20,927,000 10,646,000
General and administrative 8,999,000 6,210,000
Amortization of intangible assets 137,000 0
Total operating expenses 30,063,000 16,856,000
Loss from operations (26,033,000) (7,282,000)
Loss from remeasurement of fair value of warrants   (9,342,000)
Interest income 454,000  
Other (loss) income, net (22,000) 8,000
Loss before income tax (25,601,000) (16,616,000)
Provision for income taxes 3,226,000 0
Net loss $ (28,827,000) $ (16,616,000)
Net loss per common share, basic and diluted $ (0.45) $ (39.97)
Shares used in computing net loss per common share, basic and diluted 63,802,391 415,746