X0407 4 2023-04-24 0 0001435049 CHINOOK THERAPEUTICS, INC. KDNY 0001202785 DOBMEIER ERIC C/O CHINOOK THERAPEUTICS, INC. 400 FAIRVIEW AVE. NO., 9TH FLOOR SEATTLE WA 98109 1 1 0 0 President, CEO 0 Common Stock 2023-04-24 4 M 0 25000 0.42 A 326138 D Common Stock 2023-04-24 4 S 0 23800 21.5768 D 302338 D Common Stock 2023-04-24 4 S 0 1200 22.2592 A 301138 D Stock Option (Right to Buy) 0.42 2023-04-24 4 M 0 25000 0.00 D 2030-03-17 Common Stock 25000 313555 D The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person dated December 22, 2022. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $21.22 to $22.20, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.22 to $22.29, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth herein. The stock option vested as to 25% of the total shares monthly on March 6, 2021, and thereafter vests as to 1/48 of the total shares until fully vested, subject to the Reporting Person's provision of service to the Issuer on the vesting date. /s/ Kirk Schumacher, Attorney-in-Fact 2023-04-26