X0306 4 2022-05-27 0 0001435049 CHINOOK THERAPEUTICS, INC. KDNY 0001253170 AKKARAJU SRINIVAS C/O CHINOOK THERAPEUTICS, INC. 400 FAIRVIEW AVENUE NORTH, SUITE 900 SEATTLE WA 98109 1 0 0 0 Common Stock 2022-05-27 4 P 0 570000 14.00 A 5161888 I By Samsara BioCapital, L.P. Represents a purchase from the underwriters in a public offering of the issuer. Shares held by Samsara BioCapital, L.P. ("Samsara BioCapital"). The reporting person is a managing member of Samsara BioCapital GP, LLC, the general partner of Samsara BioCapital. The reporting person disclaims beneficial ownership of these shares except to the extent of the reporting person's pecuniary interest therein. /s/ Srinivas Akkaraju 2022-06-01