X0306 4 2016-01-08 0 0001435049 ADURO BIOTECH, INC. ADRO 0001193195 SCHAFER GREGORY W C/O ADURO BIOTECH, INC. 626 BANCROFT WAY, 3C BERKELEY CA 94710 0 1 0 0 Chief Operating Officer Common Stock 2016-01-08 4 M 0 20000 1.00 A 69279 D Common Stock 2016-01-08 4 S 0 20000 23.58 D 49279 D Stock Option (right to buy) 1.00 2016-01-08 4 M 0 20000 0.00 D 2024-07-30 Common Stock 20000 229839 D The sales reported in this Form 4 were affected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2015. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $23.135 to $24.04, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. The shares subject to the Option vest in 48 equal monthly installments from the vesting commencement date of July 31, 2014. /s/ Jennifer Lew, Attorney-in-Fact 2016-01-11