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    <periodOfReport>2022-04-04</periodOfReport>

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    <issuer>
        <issuerCik>0001435049</issuerCik>
        <issuerName>CHINOOK THERAPEUTICS, INC.</issuerName>
        <issuerTradingSymbol>KDNY</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001750266</rptOwnerCik>
            <rptOwnerName>Versant Venture Capital VII, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE SANSOME STREET</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 3630</rptOwnerStreet2>
            <rptOwnerCity>SAN FRANCISCO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94104</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
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            <isTenPercentOwner>1</isTenPercentOwner>
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        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001745960</rptOwnerCik>
            <rptOwnerName>Versant Voyageurs I, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE SANSOME STREET</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 3630</rptOwnerStreet2>
            <rptOwnerCity>SAN FRANCISCO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94104</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
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            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001745961</rptOwnerCik>
            <rptOwnerName>Versant Voyageurs I Parallel, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE SANSOME STREET</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 3630</rptOwnerStreet2>
            <rptOwnerCity>SAN FRANCISCO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94104</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
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            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
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            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
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            <deemedExecutionDate></deemedExecutionDate>
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            <transactionTimeliness>
                <value></value>
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                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
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                <natureOfOwnership>
                    <value>See Footnote</value>
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        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
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                <directOrIndirectOwnership>
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                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
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        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
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            <transactionDate>
                <value>2022-04-04</value>
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                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F7"/>
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        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
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                <sharesOwnedFollowingTransaction>
                    <value>1863197</value>
                </sharesOwnedFollowingTransaction>
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                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F9"/>
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        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
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                    <value>552149</value>
                </sharesOwnedFollowingTransaction>
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                <directOrIndirectOwnership>
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                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
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    <footnotes>
        <footnote id="F1">Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Venture Capital VII, L.P. (&quot;Versant VII&quot;) to its partners pursuant to a Rule 10b5-1 trading plan.</footnote>
        <footnote id="F2">These securities are held of record by Versant VII. Versant Ventures VII GP, L.P. (&quot;Versant Ventures VII GP&quot;) is the general partner of Versant VII, and Versant Ventures VII GP-GP, LLC (&quot;Versant Ventures VII GP-GP&quot;) is the general partner of Versant Ventures VII GP. Jerel C. Davis, a member of the Issuer's board of directors, is a managing director of Versant Ventures VII GP-GP and may be deemed to share voting and dispositive power over the shares held by Versant VII. Each of Versant Ventures VII GP-GP, Versant Ventures VII GP and Jerel C. Davis disclaims beneficial ownership of the shares held by Versant VII, except to the extent of their respective pecuniary interests therein. Jerel C. Davis is a director of the Issuer and, accordingly, files separate Section 16 reports.</footnote>
        <footnote id="F3">Represents a change in the form of ownership of Versant Ventures VII GP by virtue of the receipt of shares in the pro-rata in-kind distribution of common stock of the Issuer for no consideration by Versant VII.</footnote>
        <footnote id="F4">Shares held by Versant Ventures VII GP. Versant Ventures VII GP-GP is the general partner of Versant Ventures VII GP. Jerel C. Davis, a member of the Issuer's board of directors, is a managing director of Versant Ventures VII GP-GP and may be deemed to share voting and dispositive power over the shares held by Versant Ventures VII GP. Each of Versant Ventures VII GP-GP and Jerel C. Davis disclaim beneficial ownership of the shares held by Versant Ventures VII GP, except to the extent of their respective pecuniary interests therein. Jerel C. Davis is a director of the Issuer and, accordingly, files separate Section 16 reports.</footnote>
        <footnote id="F5">Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Ventures VII GP to its partners.</footnote>
        <footnote id="F6">Represents a change in the form of ownership of Versant Ventures VII GP-GP by virtue of the receipt of shares in the pro-rata in-kind distribution of common stock of the Issuer for no consideration by Versant Ventures VII GP.</footnote>
        <footnote id="F7">Shares held by Versant Ventures VII GP-GP. Jerel C. Davis, a member of the Issuer's board of directors, is a managing director of Versant Ventures VII GP-GP and may be deemed to share voting and dispositive power over the shares held by Versant Ventures VII GP-GP. Jerel C. Davis disclaims beneficial ownership of the shares held by Versant Ventures VII GP-GP, except to the extent of his pecuniary interests therein. Jerel C. Davis is a director of the Issuer and, accordingly, files separate Section 16 reports.</footnote>
        <footnote id="F8">Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Ventures VII GP-GP to its members.</footnote>
        <footnote id="F9">These securities are held of record by Versant Voyageurs I, L.P. (&quot;Versant Voyageurs I&quot;). Versant Voyageurs I GP Company is the general partner of Versant Voyageurs I. Jerel C. Davis, a member of the Issuer's board of directors, is a director of Versant Voyageurs I GP Company and may be deemed to share voting and dispositive power over the shares held by Versant Voyageurs I. Each of Versant Voyageurs I GP Company and Jerel C. Davis disclaims beneficial ownership of the shares held by Versant Voyageurs I, except to the extent of their respective pecuniary interests therein. Jerel C. Davis is a director of the Issuer and, accordingly, files separate Section 16 reports.</footnote>
        <footnote id="F10">These securities are held of record by Versant Voyageurs I Parallel, L.P. (&quot;Versant I Parallel&quot;). Versant Voyageurs I GP, L.P. (&quot;Versant Voyageurs I GP&quot;) is the general partner of Versant I Parallel. Versant Ventures VI GP, L.P. (&quot;Versant Ventures VI GP&quot;) is the general partner of Versant Voyageurs I GP. Versant Ventures VI GP-GP, LLC (&quot;Versant Ventures VI GP-GP&quot;) is the general partner of Versant Ventures VI GP. Jerel C. Davis, a member of the Issuer's board of directors, is a managing director of Versant Ventures VI GP-GP and may be deemed to share voting and dispositive power over the shares held by Versant I Parallel. Each of Versant Ventures VI GP-GP, Versant Ventures VI GP, Versant Voyageurs I GP and Jerel C. Davis disclaims beneficial ownership of the shares held by Versant I Parallel, except to the extent of their respective pecuniary interests therein. Jerel C. Davis is a director of the Issuer and, accordingly, files separate Section 16 reports.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Robin L. Praeger, Managing Director of Versant Ventures VII GP-GP, LLC, general partner of Versant Ventures VII GP, L.P., general partner of Versant Venture Capital VII, L.P.</signatureName>
        <signatureDate>2022-04-06</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Robin L. Praeger, President of Versant Voyageurs I GP Company, general partner of Versant Voyageurs I, L.P.</signatureName>
        <signatureDate>2022-04-06</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Robin L. Praeger, Managing Director of Versant Ventures VI GP-GP LLC, general partner of Versant Ventures VI GP, L.P., general partner of Versant Voyageurs I GP, L.P., general partner of Versant Voyageurs I Parallel, L.P.</signatureName>
        <signatureDate>2022-04-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
