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Stock Compensation (Tables)
 12 Months Ended
Dec. 31, 2025
Share-Based Payment Arrangement [Abstract]  
Summary of Activity Relating to the Company's Options to Purchase Common Stock
The following table summarizes the activity relating to the Company’s options to purchase common stock for the year ended December 31, 2025:
Weighted-Average
Weighted-AverageRemaining
Number ofExercise PriceContractualAggregate
OptionsPer ShareTerm (Years)Intrinsic Value
(in thousands)
Outstanding at December 31, 20245,177,511 $8.70 7.43$480 
Granted2,581,040 $1.74 
Forfeited or cancelled (vested and unvested)(891,000)$11.22 
Exercised
(89,660)$1.91 
Outstanding at December 31, 20256,777,891 $5.81 7.49$7,999 
Vested and expected to vest at December 31, 20256,777,891 $5.81 7.49$7,999 
Exercisable at December 31, 20253,498,581 $9.27 6.44$2,525 
The following table summarizes the activity relating to the Company’s performance-based stock options for the year ended December 31, 2025:
Weighted-Average
Weighted-AverageRemaining
Number ofExercise PriceContractualAggregate
PBSOsPer ShareTerm (Years)Intrinsic Value
(in thousands)
Outstanding at December 31, 2024632,950 $4.97 6.35$123 
Forfeited or expired
(144,800)$6.52 
Exercised
(44,650)$1.62 
Outstanding at December 31, 2025443,500 $4.80 6.80$330 
Vested and expected to vest at December 31, 2025443,500 $4.80 6.80$330 
Exercisable at December 31, 2025443,500 $4.80 6.80$330 
Schedule of Weighted-Average Assumptions Used to Compute the Stock-Based Compensation Costs for the Stock Options Granted to Employees
The following table shows the weighted-average assumptions used to compute the stock-based compensation costs for the stock options granted to employees during each of the two years ending December 31, 2025, using the Black-Scholes option-pricing model:
Year ended
December 31,
202520242023
Risk-free interest rate3.94%4.33%3.83 %
Dividend yield— — — 
Weighted-average expected life of options (years)5.956.136.17
Volatility84%85%79 %
Summary of Activity Relating to the Company's RSUs
The following table summarizes the activity relating to the Company’s RSUs for the year ended December 31, 2025:
Number ofWeighted-Average
RSUsFair Value Per Share
Outstanding and unvested at December 31, 20244,447,074 $2.83 
Granted6,096,016 $1.67 
Forfeited or expired(808,410)$2.21 
Vested(2,627,262)$2.65 
Outstanding and unvested at December 31, 20257,107,418 $1.97 
Summary of Total Stock Based Compensation Expense
The following table summarizes the total stock-based compensation expense in each of the income statement line items for the years ended December 31, 2025, 2024 and 2023:
Year ended December 31,
202520242023
(in thousands)
Research and development$1,543 $2,232 $3,430 
Selling, general and administrative8,327 9,761 8,528 
Total stock compensation expense
$9,870 $11,993 $11,958