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Collaborations with Third Parties (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Jan. 02, 2024
Apr. 17, 2020
Jan. 02, 2019
Apr. 30, 2021
Mar. 31, 2025
Mar. 31, 2024
Dec. 31, 2020
Collaborations with Third Parties              
First milestone payment $ 100,000            
Time required to pay cash portion 15 days            
Second milestone payment $ 25,000            
Total Revenues         $ 64,995 $ 137,735  
Royalty Revenue From DSE And Sale Of Bulk Tablets And Milestones Received              
Collaborations with Third Parties              
Total Revenues         29,400 113,000  
Collaboration revenue              
Collaborations with Third Parties              
Total Revenues         30,082 112,979  
Minimum              
Collaborations with Third Parties              
Aggregate payment agreement 125,000            
Daiichi Sankyo Europe GmbH ("DSE")              
Collaborations with Third Parties              
Cash payment $ 300,000            
Daiichi Sankyo Europe GmbH ("DSE") | Minimum | Commitment Offering              
Collaborations with Third Parties              
Royalties 15.00%            
Daiichi Sankyo Europe GmbH ("DSE") | Maximum | Commitment Offering              
Collaborations with Third Parties              
Royalties 25.00%            
Daiichi Sankyo Europe GmbH ("DSE") | License and Collaboration Agreement              
Collaborations with Third Parties              
Upfront cash payment received (paid)     $ 150,000        
Cash payment to the Company upon first commercial sales in the DSE Territory             $ 150,000
Daiichi Sankyo Europe GmbH ("DSE") | License and Collaboration Agreement | Minimum              
Collaborations with Third Parties              
Percentage of royalties to be received on the net sales     15.00%        
Daiichi Sankyo Europe GmbH ("DSE") | License and Collaboration Agreement | Maximum              
Collaborations with Third Parties              
Percentage of royalties to be received on the net sales     25.00%        
Otsuka Pharmaceutical Co, Ltd. | Collaboration revenue              
Collaborations with Third Parties              
Total Revenues         0 0  
Otsuka Pharmaceutical Co, Ltd. | Exclusive Developmental Activities              
Collaborations with Third Parties              
Upfront cash payment received (paid)   $ 60,000          
Potential additional future payments   450,000          
Proceeds from milestone upon submission of a Japanese New Drug Application (JNDA) in the Otsuka Territory   $ 10,000          
Otsuka Pharmaceutical Co, Ltd. | Exclusive Developmental Activities | Minimum              
Collaborations with Third Parties              
Percentage of royalties to be received on the net sales   15.00%          
Otsuka Pharmaceutical Co, Ltd. | Exclusive Developmental Activities | Maximum              
Collaborations with Third Parties              
Percentage of royalties to be received on the net sales   30.00%          
Milestone payment upon JNDA Approval in the Otsuka Territory   $ 10,000          
Milestone payment, first national health insurance price listing   70,000          
Milestone payment, achievement of the primary MACE in the CLEAR Outcomes study and CV risk reduction rate on the U.S. label   50,000          
Milestone payments related to total net sales achievements   $ 310,000          
Daiichi Sankyo Co. Ltd | Collaboration revenue              
Collaborations with Third Parties              
Total Revenues         400 $ 0  
Daiichi Sankyo Co. Ltd | License and Collaboration Agreement              
Collaborations with Third Parties              
Consideration cash payment       $ 30,000      
Payment to be received upon milestone       $ 175,000      
Daiichi Sankyo Co. Ltd | License and Collaboration Agreement | Minimum              
Collaborations with Third Parties              
Percentage of royalties to be received on the net sales       5.00%      
Daiichi Sankyo Co. Ltd | License and Collaboration Agreement | Maximum              
Collaborations with Third Parties              
Percentage of royalties to be received on the net sales       20.00%      
Neopharm | License and Collaboration Agreement              
Collaborations with Third Parties              
Total Revenues         $ 300