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Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Operating activities    
Net loss $ (209,248) $ (233,659)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 164 500
Amortization of premiums and discounts on investments (412) 279
Amortization of discount and issuance costs on convertible notes 1,697 1,621
Non-cash interest expense related to the revenue interest liability 46,679 44,590
Stock-based compensation expense 11,958 15,215
Changes in assets and liabilities:    
Accounts receivable (14,765) (10,795)
Prepaids and other assets 6,192 1,419
Deferred revenue 21,895 (2,810)
Inventories (30,422) (807)
Accounts payable 8,678 5,603
Other accrued liabilities 22,097 4,017
Net cash used in operating activities (135,487) (174,827)
Investing activities    
Purchases of investments 0 (59,897)
Proceeds from sales/maturities of investments 42,500 68,001
Net cash provided by investing activities 42,500 8,104
Financing activities    
Proceeds from issuance of common stock and warrants from offering, net of issuance costs 52,428 0
Proceeds from issuance of common stock from ATM Program, net of issuance costs 4,448 90,849
Proceeds from exercise of warrants 9,069 0
Proceeds from exercise of pre-funded warrants 21 0
Payments on revenue interest liability (15,506) (8,024)
Repayment of principal on revenue interest liability 0 (50,000)
Payment for other issuance costs 0 (219)
Net cash provided by financing activities 50,460 32,606
Net decrease in cash, cash equivalents and restricted cash (42,527) (134,117)
Cash, cash equivalents and restricted cash at beginning of period 124,775 258,892
Cash and cash equivalents at end of period 82,248 124,775
Supplemental disclosure of cash flow information:    
Issuance costs not yet paid 635 1
Non-cash right of use asset $ 115 $ 5