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Income Taxes - Summary (Details) - USD ($)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Provision for income taxes      
Provision for income taxes $ 0 $ 0  
Net deferred tax assets, before valuation allowance 395,600,000 352,100,000  
Unrecognized tax benefits 2,099,000 2,099,000 $ 2,099,000
Research Tax Credit Carryforward      
Provision for income taxes      
Tax credit carryforward 21,000,000    
Federal      
Provision for income taxes      
Net operating loss carryforwards 1,027,500,000 950,800,000  
Operating loss carryforwards, subject to expiration 347,400,000    
State      
Provision for income taxes      
Net operating loss carryforwards $ 696,100,000 $ 698,400,000