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The Company and Basis of Presentation (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Jan. 18, 2024
USD ($)
$ / shares
shares
Jan. 02, 2024
USD ($)
Mar. 22, 2023
USD ($)
$ / shares
shares
Mar. 19, 2023
USD ($)
$ / shares
shares
Aug. 31, 2019
patient
Dec. 31, 2023
USD ($)
$ / shares
shares
Dec. 31, 2022
USD ($)
$ / shares
shares
Dec. 31, 2020
product
Mar. 23, 2023
$ / shares
Dec. 31, 2021
$ / shares
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Products approved | product               2    
Number of study patients | patient         14,000          
Common stock, shares issued (in shares) | shares           120,204,513 76,564,396      
Common stock, par value (in dollars per share)           $ 0.001 $ 0.001      
Proceeds from issuance of common stock, net of issuance costs | $           $ 4,448 $ 90,849      
Subsequent Event                    
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Common stock, par value (in dollars per share) $ 0.001                  
Net proceeds | $ $ 90,800                  
First milestone payment | $   $ 100,000                
Time required to pay cash portion   15 days                
Second milestone payment | $   $ 25,000                
Subsequent Event | Minimum                    
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Aggregate payment agreement | $   $ 125,000                
Underwritten Public Offering | Subsequent Event                    
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Common stock, par value (in dollars per share) $ 0.001                  
Exercise price (in dollars per share) $ 1.50                  
Net proceeds | $ $ 90,800                  
Issued stock (in shares) | shares 56,700,000                  
Price per share (in dollars per share) $ 1.50                  
Over Allotment Option | Subsequent Event                    
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Issued stock (in shares) | shares 8,505,000                  
Option period 30 days                  
Securities Purchase Agreement                    
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Common stock, shares issued (in shares) | shares       12,205,000            
Common stock, par value (in dollars per share)       $ 0.001            
Common stock purchasable under prefunded warrants (in shares) | shares       20,965,747            
Common stock purchasable under warrants (in shares) | shares       33,170,747            
Exercise price (in dollars per share)           $ 1.55        
Securities Purchase Agreement | Common Stock And Accompanying Warrant                    
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Purchase price (in dollars per share)       $ 1.675            
Securities Purchase Agreement | Pre Funded Warrant And Accompanying Warrant                    
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Purchase price (in dollars per share)       $ 1.674            
Warrant Amendment Agreements                    
Organization, Consolidation and Presentation of Financial Statements [Line Items]                    
Common stock purchasable under warrants (in shares) | shares     9,024,212              
Exercise price (in dollars per share)     $ 1.55     $ 1.55     $ 1.55 $ 9.00
Expiration term                 3 years 6 months  
Additional consideration (in dollars per share)     $ 0.125              
Net proceeds | $     $ 55,500 $ 1,200            
Proceeds from issuance of common stock, net of issuance costs | $       $ 51,300            
Proceeds from warrant amendment | $     $ 1,100