Commitments and Contingencies (Details) - USD ($) $ in Millions	May 04, 2023	Mar. 27, 2023	Mar. 04, 2023
Loss Contingencies [Line Items]
Partner milestone payments		$ 300	$ 300
Subsequent Event
Loss Contingencies [Line Items]
Partner milestone payments	$ 300
Cardiovascular Risk | Minimum
Loss Contingencies [Line Items]
Percentage of risk reduction		20.00%	15.00%
Cardiovascular Risk | Maximum
Loss Contingencies [Line Items]
Percentage of risk reduction			20.00%
Cardiovascular Risk Outcome Less than Twenty Percent | Minimum
Loss Contingencies [Line Items]
Partner milestone payments			$ 200
Cardiovascular Risk Outcome Greater than Twenty Percent | Maximum
Loss Contingencies [Line Items]
Partner milestone payments			$ 300
Relative Risk
Loss Contingencies [Line Items]
Percentage of risk reduction			20.00%