Net Loss Per Common Share - Calculation of diluted net loss per share (Details) - shares	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Net Income (Loss) Per Common Share
Total potential dilutive shares (in shares)	51,570,226	49,670,635
Common shares under option
Net Income (Loss) Per Common Share
Total potential dilutive shares (in shares)	3,842,737	3,214,537
Unvested RSUs
Net Income (Loss) Per Common Share
Total potential dilutive shares (in shares)	1,768,185	698,704
Shares issuable related to the ESPP
Net Income (Loss) Per Common Share
Total potential dilutive shares (in shares)	27,558	23,448
Unvested PBRSUs
Net Income (Loss) Per Common Share
Total potential dilutive shares (in shares)	461,250	639,950
Common shares under PBSOs
Net Income (Loss) Per Common Share
Total potential dilutive shares (in shares)	499,200	122,700
Shares issuable upon conversion of convertible notes
Net Income (Loss) Per Common Share
Total potential dilutive shares (in shares)	8,007,010	8,007,010
Warrants for common stock
Net Income (Loss) Per Common Share
Total potential dilutive shares (in shares)	36,964,286	36,964,286